Webinar: A Systematic Approach for Driving Cell Identity and Accelerating Regenerative Medicine

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Webinar: A Systematic Approach for Driving Cell Identity and Accelerating Regenerative Medicine

2020  |  Aida Moreno-Moral, Pierre-Louis Joffrin

Despite the 2007 discovery for converting a somatic cell into an induced pluripotent stem cell (iPSC) using transcription factors (TFs), the requirement to recapitulate biological pathways in the reprogramming of iPSCs and inability to optimize through experimental trial and error has proved limiting. In any given cell, thousands of genes are expressed at any given time. The number of possible combinations exceeds the number of stars in the galaxy, rendering even high-throughput approaches impractical.

In this webinar, we explore how new approaches (such as high-resolution data and novel computational algorithms) can enhance existing stem-cell forward reprogramming methods, bypass development pathways altogether for the development of ex vivo cell therapies – and facilitate an entirely new class of in vivo reprogramming therapies.

In this webinar-on-demand, Dr. Aida Moreno-Moral, Principal Bioinformatician, and Pierre-Louis Joffrin, Corporate Development Officer, discuss:
• The challenges associated with the delivery of cell therapies
• How harnessing computational biology will drive the development of future cell therapies
• Applying Mogrify® to transform ex vivo cell therapies and pioneer a new class of in vivo reprogramming.

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